Sentence examples for modelled structures the from inspiring English sources

Thus, based on the modelled structures, the mechanism of protein-biomolecule interactions at the active site seems to be completely different for the three proteins, and then, we hypothesize that different recognition sites should be present in the three proteins.

The modelled structures of the three proteins show the well-known TRX fold.

A comparison of the modelled structures of the C-domains in the apoprotein and p[NH]ppA-bound states revealed domain motions induced by p[NH]ppA binding.

We finally used the modelled structures of the S. mansoni glucose transporters to biophysically (i) analyze the dynamics of key residues during glucose binding, (ii) test glucose stability within the active site, and (iii) demonstrate glucose diffusion.

The crystal structure of the extracellular loop 1 (ECL1) of the human smoothened receptor (Table 1) was used to predict the structure of the ECL1 of the three modelled structures of the TSHR TMD (Table 1).

On the other hand, the SNP effects on protein functions were inferred by modelled structures because the molecular modelling method has been found useful for estimating the effects of the substitution of amino acid residues on protein function.

Thus, the relationship between primary and tertiary structure is robust (as shown by the agreement among the three TRX modelled structures), but the link between biophysical features and primary structure is not conserved among TRXs, and it seems that there is not a direct relationship.

We also modelled structures of the TMDs of the FSHR and LH receptor (LHR) in their active and inactive conformations.

Some alternative in silico techniques to construct pMHC complexes have already been developed (14 16), but the question relying above all current available approaches is how reliable are these modelled structures, considering the importance of the information that they carry?

A thorough empirical evaluation on computationally predicted structures of biological sequences and artificially generated RNA structures as well as on empirically modelled structures from the biological literature shows that RNA-SSD substantially outperforms the best known algorithm for this problem, RNAinverse from the Vienna RNA Package.

In silico analysis of these genes as well as modelled structures of the putative BBP proteins are presented.