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Appropriate costs and quality of life weights were attached to modelled events and health states, allowing cumulative health and social care costs and quality adjusted life years (QALYs) to be modelled over time.
In addition to the capital and operating costs, techno-economic characteristics such as electrical efficiencies (LHV% basis), Levelised Cost of Electricity (LCOE), costs of CO2 captured and CO2 avoided were modelled over time assuming technology improvements from today to 2050.
Rather than one large table to be modelled over time we considered each disease group separately.
This dynamic decision analytic technique allows the progression from LTBI to active TB and the treatment outcome to be modelled over time.
Our analysis showed that there were problems in the factor structure of GHQ when used as a simple score, but they disappear when modelled over time.
Figure 4 provides an overview of the main interventions modelled over time, emphasising that decolonisation and vaccination are more recent subjects of study.
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We did this within a multiple imputation framework (using five imputations) to account for uncertainty in the modelled changes over time.
A typical compartmental model is described by a nonlinear system of ordinary differential equations (ODEs) governing changes in the number (or proportions) of individuals in pre-specified subgroups of the modelled population over time.
A simple adjustment of outdated BMIs based on our modelled changes over time brought the CPRD mean BMI statistics in line with the HSE estimates, and when we validated the adjustment in a subset of patients with repeated BMI measures, we found smaller errors on average, compared with simply carrying outdated BMI records forwards.
"People change over time.
From these modelled time-inverse characteristics, time dial settings (TDS) and operating time of the over current relays are calculated.
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