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Individual plasticity in laying date was modelled including only two of three environmental variables that were significant in the population-level analysis (i.e. spring temperature, breeder density; see Results).
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The reduced frequency MSEs include only modelled data and so are suitable for the experimental validation of the simulation.
It included only acting.
Include only relevant information.
Include only your best references.
Include only the bare minimum.
PrP selection strategies modelled included selection against the VRQ allele and in favour of the ARR allele.
The proportion of positivity assay results was modelled (R package version 3.1.2) using a generalised linear model (glm) with a logit link (logistic regression model) fitted to two covariate models including stage and lesion or stage only.
Numerically, the net health effect was moderate, which was partly due to the modelled scenario only including a relatively small population.
Only if the prognostic model includes all variables significantly affecting outcome and if these are well defined and modelled appropriately can the model be used for performance evaluations.
The majority of models (26 of 37) incorporated adverse events; 23 models included adverse events as an outcome leading to treatment discontinuation; only 3 studies [ 8, 9, 39] modelled the impact of individual adverse events in terms of utility and costs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com