Sentence examples for modelled in vitro from inspiring English sources

We modelled in vitro a scenario in which we utilized supra-pharmacological doses of cisplatin and paclitaxel [ 25, 26] to maximize the cytotoxicity of the drugs, but limited their effect to clinically relevant times.

Here, we used segregated XY and XX primary cerebellar granule neuronal cultures that are either WT (wild-type) or Parp-1 KO, modelled in vitro using transient OGD (oxygen-glucose deprivation), to examine sex-related differences in the activation of both intrinsic- and extrinsic-cell death pathways.

Lipotoxicity was modelled in vitro using hepatocytes derived from WT and caspase-2-deficient mice.

An interesting feature of muscle fiber cellularization is that it can be modelled in vitro using skeletal muscle myotubes [20].

Both 3'-processing and strand transfer reactions can be modelled in vitro with the recombinant IN and short oligodeoxynucleotides (ODN) mimicking the extremities of the viral genome.

Spermatogenesis is a complex process that cannot, as yet, be modelled in vitro [8], involving mitotic proliferation, meiotic division and spermiogenesis, followed by release of mature sperm and taking 35 days in mice (75 days in human)[49].

Such heterogeneity is not easily modelled with in vitro studies.

This requires demonstrating that the relevant specific neurodevelopmental effect is modelled adequately in vitro.

These effects were at variance from d-sotalol, a selective IKr blocker, despite prolongation of action potential duration and the QT interval of the in-vitro-modelled electrocardiogram by both drugs.

Although it has been suggested that microgravity might affect drug absorption in vivo, drug permeability across epithelial barriers has not yet been investigated in vitro during modelled microgravity.

"In vitro models are cleaner".