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PDB IDs: the coordinates for the modelled and refined E. coli tmRNA has been deposited in the Protein Data Bank with accession numbers: 3IZ4.
After merging 281 diffraction patterns and phasing by molecular replacement, we produced a density map at 2.5 Å resolution and modelled and refined the structure of AQP0 (residues 7 226) in the membrane junction.
We modelled and refined the tertiary structure of LPKC using computational methods such as homology modelling and molecular dynamics simulations.
Compare with Fig. 13 which shows the corresponding S S bridge in chain C 3) in which atom Sγ11 is disordered into two sites A (80%) and B (20%) and Fig. 16 which shows the electron density in this region in Intergen (II) which has been modelled and refined as a single ordered cysteine but appears, in fact, to be an ordered double conformation as in Intergen (I).
Protein residues 7 226 were visible and were modelled and refined.
It was modelled and refined in analogue studies and exploratory trials in the 1960s (e.g., [ 13]); with definitive randomised controlled trials being conducted in the 1970s (e.g., [ 14]) and long term implementation studies conducted over the last twenty years [ 15, 16].
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JH prepared and refined working data sets from primary data, also modelled care groups from re-imbursement data.
And refined it is.
Comfortable and refined, getting dated now.
All is relatively calm and refined.
His interpretations were considered elegant and refined.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com