We modelled these mutations in the VP1 pocket to explain their effect on the binding mode of the pocket factor and calculated the ΔΔGfolding of these mutants.
We modelled prostate cancer-specific death as a function of MUC-1 levels accounting for age, Gleason grade and tumour extent, and calculated age-adjusted and multivariate adjusted hazard ratios (HR).
The data analysis was performed and modelled to calculate ORs and 95% CIs using SAS version 9.13 software (SAS Institute Inc., Cary, NC).
SNPs and genes were modelled (and odds ratios calculated) using logistic regression with disease status as outcome variable and allele(s), assuming multiplicative allelic effects, as independent variable(s).
Variations in weight, energy and nutrients in observed and modelled diets were calculated for each food group (n = 7), with a focus on dairy products.
The atmospheric radiative transfer simulator (ARTS2) (Eriksson et al. 2011) is used as forward model to simulate atmospheric radiative transfer and calculate an ozone spectrum for the modelled atmosphere by using an a priori ozone profile.
The modelled changes were calculated by subtracting the 2050s prediction from directly comparable modelled present day climate following Peterson et al. [ 24] and IPCC recommendations [ 57].
The solvent accessibilities of the amino acid residues in a 3D modelled structure were calculated using a modification of the Shrake and Rupley method, with a water molecule represented by a 1.4 Å radius sphere.
How clever and calculating.
Modelled values were calculated for each 1 km grid cell within the study area and assigned to the residential addresses of the participants (ArcView 9.2).
