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In this commentary we provide an overview of the challenges that arise from applying molecular modeling tools developed and commonly used for pharmaceutical discovery to the problem of predicting the potential toxicities of environmental chemicals.
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In order to fill this gap, this paper proposes a Service Engineering framework that integrates a product-service design modelling tool developed at the Tokyo Metropolitan University with a discrete event simulation test-bench, which enables the comparison of several PSS configurations and the evaluation of both customer and internal performance.
In order to fill this gap, this paper proposes a Service Engineering framework that integrates a product-service design modelling tool developed at the Tokyo Metropolitan University with a discrete event simulation test-bench, enabling the comparison of several PSS configurations considering both customer satisfaction measures and internal performance.
An interdisciplinary analysis of problems and adequate hydrological modelling tools developed by geologists, hydrologists and biologists are necessary.
High-resolution neighbourhood-scale modelling tools developed to account for the complex three-dimensional surfaces and volumes within an urban area are able to predict temperature perturbations over an urban domain with reference to varying land-use.
The data analysis was performed using R [31] and the generalized additive model tools developed by Wood [32], [33].
It is proposed that a process modeling tool be developed specifically to support simulation requirements gathering.
This can be achieved through an innovative combination of toxicology, risk assessment modeling, and tools developed in the field of multicriteria decision analysis (MCDA).
In order to confirm that ERα36 can trigger the progression of breast cancer in the primary tumor as well as during metastasis and to characterize the underlying mechanisms of high ERα36-dependent phenotypes, we developed modeling tools.
An iterative, SimpleScalar based architectural modeling tool has been developed to analyze various parameters of superscalar processors.
The SHERPA (Screening for High Emission Reduction Potentials on Air quality) modelling tool was developed in this context.
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