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Critical for their use in modeling the developmental neurotoxicity of CPF, PC12 cells differentiate specifically into two phenotypes, cholinergic and catecholaminergic (Fujita et al. 1989; Teng and Greene 1994).
Furthermore, in modeling the developmental stages of BP – from non-specific symptoms, followed by minor mood disorder, major depressive episodes, and finally hypo/manic episodes – once entering the model, these high-risk offspring progressed linearly through the stages without skipping any stage (Duffy et al., 2014), which suggests a progressive process and an urgent need for intervention.
Critical for the use of PC12 cells in modeling the developmental neurotoxicity of compounds such as the organophosphates, the cholinergic and catecholaminergic phenotypes are among the prominent in vivo targets for these compounds (Aldridge et al. 2005; Barone et al. 2000; Dam et al. 1999; Jameson et al. 2006b; Pope 1999; Rice and Barone 2000; Slotkin 2004a; Slotkin et al. 2002; Vidair 2004).
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The secondary objective was to model the developmental patterns of M50, M70 and M100 in AEF.
Hence it is possible that the 56 genes may be good candidates for modeling the human developmental process.
These repeated measures may introduce a level of bias into the results presented here, and therefore, greater care would be required to model the observed developmental patterns.
Data presented here will aid in the design of future experiments using stem cells to study the transcriptional processes driving differentiation, and model the developmental impact of teratogens.
In this study, firing experiments and ceramic analysis are used in conjunction with excavation evidence to evaluate competing ideas about the buff ware manufacturing process, investigate where the pots were made, and model the developmental history of red-on-buff production.
Then, for developing classification models, the developmental toxicity data set was divided in two classes, i.e. non developmental toxicant (N) and developmental toxicant (D), as indicated in Table 7. Class N merges the first two FDA categories A and B, and the class D includes all compounds belonging to categories C, D and X.
Political economic studies of this success have highlighted a possible alternative state model – the Developmental State (DevS).
It models the developmental transition to hand preshape based on visual information (Von Hofsten and Ronnqvist 1988; Schettino et al. 2003; Witherington 2005) and utilizes the "virtual finger hypothesis" for hand control during grasping.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com