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In a previous work we designed a mimetic peptide possessing a significant aggregation modulating effect by means of a molecular modeling study, using a pentameric model as a molecular target.
A molecular modeling study using density functional theory was carried out in order to get an insight of the thermodynamics and mechanisms for NH3 evolution during the reaction of hydrogen with nitrogen containing carbonaceous materials using pyridinic nitrogen species as a model.
Only if the difference in health between the treatment arms appears not to be stable over time, an additional modeling study using a Markov model will be performed.
If the course of OA (and its related costs) appears to fluctuate (particularly if the difference between treatment arms is not stable over time), an additional modeling study using a Markov model will be performed.
A mathematical modeling study using data from the iPrEx trial showed that two doses per week would correspond to a 76 % reduction in HIV infections, while four and seven doses a week would correspond to 96 and 99 % reduction, respectively [ 24].
The average costs for physician visits per acute asthma episode were estimated to range from $31.72 [ 34] in an economic modeling study using prospectively collected resource utilization data (9/1/94 to 8/31/95) from hospital emergency department visitors to $31.91 in the economic analysis by Seung and Mittmann [ 42].
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Those preliminary studies inspired more-extensive disease modeling studies using iPSCs.
A cost-effectiveness modelling study using data collected between February 2005 and November 2007 from a cluster-randomised trial that compared Telephone Counselling with a "Usual Care" (brief intervention) alternative.
Modeling studies using a known MMP-12 crystal structure identified a new interaction mode for these new MMP-12 inhibitors.
We assessed molecular modeling on COX-2 protein by standard computer modeling studies using MOE 2007.09 (Chemical Computing Group Inc., Köln, Germany).
A model study using glass slides and polypropylene films was conducted to confirm the feasibility of treatment.
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