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Molecular modeling studies identified the possible interaction of compound 8c with the molecular target by forming topoisomerase/DNA/drug ternary complex.
Molecular modeling studies identified a putative binding site for SA-17 in the DENV glycoprotein E (Kaptein et al., submitted for publication).
All health economic (modeling) studies identified were assessed for quality using the Drummond checklist.
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Both these experimental and computational modeling studies have identified key criteria for the prototype reactor being designed for bulk polysilicon growth.
Site-directed mutagenesis, biochemical and molecular modeling studies have identified key amino acid residues such as Thr192 and Asn382 in the binding of agonists to M1 receptors \Huang, X.P., Nagy, P.I., Williams, F.E., Peseckis, S.M., Messer, W.S., Jr., 1999.
Molecular modeling studies have identified a hydrophobic pocket that may bind to the P1 hydrophobic residue, and Arg296 also may form a salt bridge with a charged P1' residue, which may help explain BACE1's unique substrate preferences [18].
These findings suggest that motoneuron activity contributes to the initiation of each cycle of rhythmic activity, and that motoneuron and/or R-interneuron synapses are a plausible site for the activity-dependent synaptic depression that modeling studies have identified as a critical mechanism for cycling within an episode.
A key process in angiogenesis is cellular self-organization, and previous modeling studies have identified mechanisms for producing networks and sprouts.
Based on molecular modeling studies that identified surface aromatics previously deemed nonessential for enzyme function, F54 of yCDtriple was selected for mutagenesis to an amber nonsense codon for pAzF incorporation.
If this is indeed the case, it is important for future modeling studies to identify what are these important factors that must to be taken into account.
There were 18 studies identified.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com