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The modeling studies described here suggest that the N-terminus of Ets-1 remains essentially disordered upon binding to ERK2 and engages the DRS of ERK2.
The results of our mathematical modeling studies described in this paper suggest that higher levels of dedifferentiation substantially reduce the effectiveness of therapy directed at cancer stem cells.
The top 30 compounds were redocked in Glide (Schrodinger) and these coordinates used for the modeling studies described herein.
However, considering the results from modeling studies described above, contact stress might increase as a function of increased cup inclination in cases with severe pelvic tilt after THA in this group as well.
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Surprisingly, there are only three modeling studies describing the mechanism of CDI transmission, each providing insight but with important limitations.
Conducting modeling studies describing the mechanisms behind the onset and progression of these complications, as well as possible intervention points to prevent acute and chronic complications and that limit risk through self-management, would have a significant impact.
To conclude, the results of the modeling study described here indicate that HGT can prevent the operation of Muller's ratchet, and this effect can be enhanced by population subdivision.
A number of field and modeling studies have described complex interactions between permafrost degradation and the expression and behavior of hydrological processes in boreal settings due to warming temperatures, greater snowpacks, and the effects of fire and vegetation succession (Jones and others 2005); (Jorgenson and Osterkamp 2005); (Osterkamp and others 2009).
In this work, an experimental and modeling study is described, focusing on the performance of a Pd Ag membrane reactor recently proposed and suitable for the production of ultra-pure hydrogen.
Thus, while numerous studies described above have shown patterns similar to those described herein, only a few have employed a modeling approach to detect presence of pest species (Negron 1998; Negron and Popp 2004).
Molecular modeling studies are also described.
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