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In this multiscale modeling procedure, we employ an active learning strategy based on Gaussian process regression (GPR) to minimize the number of expensive DPD simulations, where adaptively selected DPD simulations are performed only as necessary.
For the expression profile modeling procedure, we first applied the low entropy filer and then have removed the ribosome-related genes by removing all genes that are annotated to belong to these two GO categories: (i) 5840, annotation= ribosome" and (ii) 5842, annotation= cytosolic large ribosomal subunit (sensu Eukaryota)".
In the IMP modeling procedure we perform a large number of independent modelling runs, each starting from a random starting configuration and undergoing thousands of rounds of small random model perturbations, in order to achieve full sampling of conformational space.
In the IMP modeling procedure we perform a large number of independent modeling runs, each starting from a random configuration and undergoing thousands of rounds of small random model perturbations, in order to achieve exhaustive sampling of conformational space.
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We have selected ARIMA modeling procedure and we have implemented it with the aid of Box-Jenkins methodology.
Metabolite and reaction compartmentation is important for a realistic representation of the mammalian cell metabolism, but determining it is more challenging both concerning experimental and modeling procedures, as we have already reviewed in [ 24].
Considering the rather simplified modeling procedure used here (recall we only solve for 1953 parameters), these misfits are of reasonable magnitudes.
This SFR model is a simplified equivalent model, and its modeling procedure is based on the generator parameters.
To construct velocity structure models for 3D FDM simulations, we adopted the modeling procedure used in Yoshimoto and Takemura (2014a).
54 During the modeling procedure, 20 homology models were generated independently, and for each model all side chain conformations were sampled three times.
We developed a modeling procedure that utilized hypothetical stand characteristics to examine lidar profiles.
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