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Our modeling procedure provides insights into ongoing outbreaks that may facilitate real-time public health responses.
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The quality of the microarray data sets were analyzed using probe-level modeling procedures provided by the affyPLM package [19] in BioConductor [56].
To assess the quality of the microarray data we graphically examined the images and the distribution of probe intensities for each array and used the probe-level modeling procedures provided by affyPLM [19] in Bioconductor including the images of the weights and residuals, normalized unscaled errors and the relative log expression method.
Details about the template used in the modeling procedure are provided.
"This procedure provides immediate gratification.
The dasymetric procedure provided a much more certain location-to-environment relationship for modeling purposes and was superior to the alternative use of average environmental conditions at the county or municipal levels.
The novelties of the modeling procedure proposed, together with the benefits provided by the FRP reinforcement, were presented and discussed in detail.
We thank Dr. James Fraser and Dr. Tom Lisney for help in optimizing the ERG experimental apparatus and procedures, Dr. William Nelson and Dr. Nikolaus Troje for suggestions regarding modeling procedures, Dr. Chris Hofmann for providing lens transmission data for cichlids, and Dr. Karen Carleton for qPCR primer sequences and helpful suggestions for gene expression analysis.
Next, the general techniques of optimization that allow automation of the modeling procedure are described.
Whichever modeling procedure is used -- whether robust Poisson or Cox, or log-binomial models --, the Prarelyly accomplishes its purpose in providing a meaningful estimate within the potential outcomes model framework.
The modeling procedure was developed based on the five Organization for Economic Cooperation and Development OECDD) principles for QSAR models.
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