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Exposure modeling of engineered nanomaterials requires input parameters such as sedimentation rates and heteroaggregation rates.
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We describe a methodology to obtain three-dimensional models of engineered surfaces using scanning electron microscopy and multi-view photogrammetry (3DSEM).
This effect was also seen in a more complex model of engineered heart tissue and correlated positively with cardiac relaxation in vitro.
As indicated in the Introduction section, the first models of engineered underdominance (Davis et al. 2001; Magori and Gould 2006) predicted efficacy of a release strategy simply based on the minimum allelic frequencies of transgenes that resulted in future increases in frequency of those transgenes in a panmictic population.
Functional modelling has been in use for a number of years for the interpretation of the results of model based simulation of engineered systems.
These include uncertainties associated with screening-level tools available for modeling deposition of engineered nanomaterials and with our understanding of characteristics and properties of materials found in the human environment.
CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration) is a recently described animal model of traumatic brain injury (TBI) that primarily produces diffuse axonal injury (DAI) characterized by white matter inflammation and axonal damage.
To gain new insights into the potential role of hnRNPs in the cholinergic contribution to Parkinsonism, we tested hippocampal RNA preparations from the brain of engineered model mice.
A novel mathematical model to simulate the growth of engineered cartilage on polymeric scaffolds performed in rotating bioreactors is proposed.
This has been permitted by the use of engineered murine models of human breast cancers where β1-integrin expression has been specifically disrupted in the mammary luminal epithelium.
Indeed, the mouse mammary gland is well suited for such studies because of the ease of recombining the epithelium and the stroma, and because of the availability of a wide variety of engineered mouse models.
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