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The PDB file for Rbp was calculated with the SWISS-Model workspace automated modeling mode using the SLT-1 A1 chain (PDB code 1dm0) as reference input [ 81].
UniProt BLAST (http://www.uniprot.org/blast/) was used to determine the identities of OsHAT proteins and HAT proteins from other organisms [ 34]. 3D comparative protein structure models of HATs were generated with the automatic modeling mode of SWISS-MODEL [ 26- 28] implemented on the SWISS-MODEL Workspace website (http://swissmodel.expasy.org/).org/
F. tularensis subsp. holarctica LVS MEP synthase (protein accession number CAJ78974) was homology-modeled using SWISS-MODEL [9] (http://swissmodel.expasy.org/) in automated modeling mode.
A numerical model of the combustor, taking account spatial non-uniformity of its temperature, was developed and employed in inverse modeling mode to derive the global combustion kinetics for polystyrene and poly(butylene terephthalate) and their blends with gas-phase active flame retardant additives.
where α is the penalty offset, ϕ si represents the selected motion modeling mode for each SI block, and T, P represent the translational and perspective motion modeling modes, respectively.
For each SI block, the motion modeling mode, ϕ si, is calculated according to: ϕ si = { P, if MA D p < MAD t - α T, if MAD p ≥ MAD t - α (15).
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Furthermore, new coding tools (such as depth-modeling mode (DMM) and segment-wise depth coding (SDC)) are exploited for the characteristics of depth map to improve the coding efficiency.
Park [30] proposed a fast depth video coding algorithm based on edge classification and depth-modeling mode omission.
Based upon the modeling binding mode of marketed AZD9291 with T790M, a series of N-9-Diphenyl-9H-purin-2-amine derivatives were designed and synthesized with the purpose to overcome the drug resistance resulted from T790M/L858R double mutations.
Based upon the modeling binding mode of marketed AZD9291 with T790M, a series of 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline derivatives were designed and synthesized with the purpose to overcome the drug resistance resulted from T790M/L858R double mutations.
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