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The low interaction energy of Arg conjugate based on molecular modeling may contribute to its enhanced cytotoxicity.
Other recently recognized aspects of hip anatomy, such as femoroacetabular impingement and hip shape as described through active shape modeling, may contribute to hip-specific OA risk [ 48- 51] while not reflecting "generalized OA".
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Workload modelling may contribute to improved health workforce planning and service efficiency.
The model may contribute to the understanding of natural wetting phenomenon and better design of related structures.
Urban growth models are widely used to anticipate future development and to inform conservation management, but the source of spatial input to these models may contribute to uncertainty in their predictions.
Since the TIR-NF-κB circuit is a conserved component of the host defence in higher animals, genetically tractable models may contribute ideas for clinical interventions.
Parental consanguinity is a risk factor for congenital heart disease (CHD) worldwide, suggesting that a recessive inheritance model may contribute substantially to CHD.
Such models may contribute to the development of tools to measure the level of risk associated with each epitope-specific autoantibody and thus prove helpful in diagnosing the disease before irreversible loss of beta cells.
Dissecting the pathways of lipid synthesis, storage and mobilization, as well as related regulatory processes, in the yeast model may contribute to the development of therapeutics and drugs against atherosclerosis, type II diabetes, obesity and other diseases related to dysfunctions of the lipid metabolism in humans.
A predictive model may contribute to the planning and decisions on long, costly human trials.
For these reasons, knowledge of the p53 pathway in other animal models may contribute critical insights into its biological functions.
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