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Some modeling groups used dynamical downscaling (with a regional climate model) to further regionalize the global climate model simulation outputs.
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Two research groups used models to estimate PM10 exposure (Table 2), although modeling methods differed.
Other variables were then entered into the model in groups using the same stepwise backward procedure, adjusting for the variable included in the precedent model.
On the basis of these models, several groups using chimeric proteins and site-directed mutagenesis have identified transmembrane (TM) domains 2, 6, 8, 9, and 10 to be important for proper function of OATP1B1.
Indeed, recent studies from different groups used mathematical models of apoptosis and applied them to cancer cells [ 19- 21].
Both groups used xenograft models in immunodeficient animals with all the potential problems regarding the microenvironment interaction mentioned above.
Others thought the paper's notion of years-long suppression was plausible but said they could not comment on the mathematical models the group used.
Then specific age differences were assessed by comparing model parameters across groups using t-tests (Supplementary Table S7).
The objective of the present study was to identify groups of patients with similar response profiles and to construct predictive models for these groups using baseline data.
Model-based (grouped) uses a flexible parametric model using grouped age and applying Eq. 3.
Model-based (grouped) uses a flexible parametric model with grouped age and applying Eq. (2).
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