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The user can switch between the three modeling formalisms on demand and "on the fly".
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After applying the discrete modeling formalism on NF- kappa B associated BRN, its hybrid model is obtained for the BRN with help of parametric constraints.
This is an example for a question of qualitative nature that can often not directly be answered based on an interaction graph, but requires more complex (and deterministic) modeling formalisms.
The types of modeling formalism depend on such characteristics [11].
Given the range of modeling approaches available to draw from 38 the "optimal" choice, particularly related to the degree of mechanistic detail to include and modeling formalism, depends on the specific questions at hand and data available.
We have elaborated on the translation of the symbolic execution tree to the NTA modeling formalism of UPPAAL enabling a modular and configurable system timing model.
The presented methodology and the model checker Mudi have been designed to not place any restrictions on the relevantly employed modelling formalism.
We shall briefly present the major modeling formalisms below.
Both the modeling formalism based on extended finite automata and the way to represent the supervisor as extended guard conditions have been implemented in a supervisory control tool.
The main contribution of this study is to provide insight into the behavior of the structure parameter of commonly used GRN model formalisms and guidelines on how to deal with this parameter in similar optimization-based reverse-engineering procedures.
This is particularly elaborated for the logical modeling formalism.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com