However, as the choice model specification becomes more complicated and custom-built modeling is increasingly in demand, researchers working in the modeling domain are challenged to go beyond the first generation modeling practices.
This work includes numerical examples in which LW models with refined kinematics are employed in local regions while ESL models are adopted in the less critical area, and modeling domains are connected by transition zone composed of elements with node-dependent kinematics.
In most cases, this choice is made when the modeling domains are chosen and impacts the structure of the entire modeling process.
The modeling domains were different, but there is a region in the central Eastern United States where ozone estimates from all four simulations are available.
We observe that state diagrams provide higher semantic comprehension of dynamic modeling in UML when the domain is real-time and sequence diagrams are better in the case of a management information application.
Sequence comparisons and modeling showed that the endonuclease domain is similar to the GIY-YIG homing endonuclease I-TevI, which makes DSBs as a monomer (Mueller et al. 1995; Kleinstiver et al. 2013).
