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Modeling data have shown that the ability of border screening to delay global pandemic influenza is closely linked to the effectiveness of the screening process or travel restriction used.
Detailed pharmacokinetic modeling data have been published in a separate report (Rezai et al, 2011).
However, pharmacokinetic modeling data have shown that oral intakes up to 100 mg/day/adult would be required to explain the reported human circulating levels (Vandenberg et al. 2009).
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10 Our mouse model data have also shown that exenatide is effective in reversing GC-induced glucose intolerance.
In vitro cell culture studies together with sparse in vivo rat model data have shown that important cell signalling pathways are affected by RCM.
In renal cancer models, data have suggested that the PI3K/AKT/mTOR pathway could be involved in resistance to sunitinib (Makhov et al, 2012).
13 While animal model data have shown that epothilones induce a dose-limiting neurotoxicity and recovery after withdrawal of treatment, 14 there is no longitudinal pathological human data to confirm this finding.
Furthermore, while animal model data have shown that IL13 blockade inhibits AHR, this has not translated into humans with any of the biologics studied so far, indicating species differences between mice and men in the underlying mechanisms of airway hyperresponsiveness.
Because relevant atmospheric model data had been archived, it was comparatively easy to run HYSPLIT with the same information for the Te Maari eruption as would be available for an eruption today.
Modelling data has shown that testing rates need to be increased to 30% or more in order to reduce the prevalence of chlamydia [ 8].
The approaches used to model the data have their own advantages and disadvantages.
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