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Population pharmacokinetic modeling can appear complex, but the methodology is easily tested.
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Although there remain several legitimate criticisms against SIS, such as the produced model can appear to be patchy, variograms can control two-point statistical measures, cross-correlation between multiple categories is not explicitly controlled, etc., we however opted for the algorithm for some specific reasons for which SIS is chosen over any other conventional techniques (Deutsch 1998).
We then compute the "Ratio of Predictable Components" (RPC) diagnostic of Eade et al. [ 2014] to show that while individual model ensembles can appear overdispersive over 20 year periods, they are not overdispersive over 40 year periods.
With some models, certain parameters can appear to exhibit good convergence behavior.
The kind of heterotachy assumed in the MBL model [ 24] can appear artificial at first sight, but is theoretically able to capture collective rate shifts, rather than the purely site independent on-off processes of the covarion model.
The models' flesh and hair can appear to be made of plastic.
In our model simulation, some cell types can appear only when these cells interact with other cell types.
Its mathematically based models and assumptions of rational conduct can appear, to non-economists, like toys, entertaining but, by definition, of limited utility.
It is important to check the identifiability property since if a model is not correctly formulated, problems can appear in the parameter estimation.
This model assumes that a new gene can appear only once in a phylogeny and that it can further evolve through duplication and loss in the descendant lineages.
To investigate the cell fates that can appear in our model, we studied the existence of stable states and their dependence on parameter values for lateral signaling by performing a bifurcation analysis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com