However, some of the next generation of MEMS devices will be so small that the finite element models are pushed to the atomic limit where they fail, and a new type of model becomes necessary.
It is only when the data are more strongly saturated, and the taxon sampling is not sufficiently rich to reveal the true extent of saturation, that a good model becomes necessary: in such situations, only the model can correctly estimate the frequency of multiple substitutions across the alignment, thereby avoiding systematic errors.
Therefore a reform of the current framework becomes necessary.
With growing usage of numerical programmes, good models become necessary.
Moreover, an integrated approach and the development of new mathematical and computational methods, for extracting maximum information from molecular and genetic information on individuals and from other clinical data and history, as well as integrating all of this information into predictive models, become necessary for the application of the P4 medicine [ 58, 59].
Secondly, where local variograms must be estimated at a large number of locations, automatic variogram model fitting becomes necessary.
Say goodbye to the growth financing model in which it becomes necessary to open dozens of new stores every year to keep the credit revolving.
With the growing number and complexity of such models published in the scientific literature, it becomes necessary for these models to be deposited and preserved in a central repository in standard formats, and BioModels serves this purpose.
In cases where QoS of a given setup is not certain, it becomes necessary to model such an environment, which can give the idea to the network planner on how to effectively write policies.
