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Experimental results were validated using the proposed analytical models and FE modeling, and were observed to be in good agreement.
Easily accessible variables that are common and standard in most ED practices were used as candidate variables for regression modeling and were retrieved from a variety of sources (Table 2).
Truncation points were chosen based on transmembrane topology modeling and were predicted to delete one or two transmembrane segments from either end of the Hhat polypeptide (Fig. 1A).
These gene models were specifically excluded from the final round of automated gene modeling and were addressed separately.
J Myers, R Wielage, and J Gahn are employees of Medical Decision Modeling and were contracted by Eli Lilly and Co. to conduct this study.
No other medications (e.g., antihistamines, analgesics, antihypertensives) were used with a frequency or regularity that permitted analysis or modeling and were considered essentially as part of the inherent variability in any human study.
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