Sentence examples for modeling and structure from inspiring English sources

The most reliable technique for such modeling and structure prediction is comparative modeling (18).

In this chapter we will introduce the commonly used methods for protein modeling and structure prediction, with a particular emphasis on the comparative or homology modeling approaches that are widely used in drug discovery and design.

Firstly, we performed homology modeling and structure validation of the BRP44 protein.

These include automating training sets selection to increase functional coverage, coupling FEATURE to structural diversity generating methods such as molecular dynamics simulations and loop modeling methods to improve performance, and using FEATURE in large-scale modeling and structure determination efforts.

The homology modeling and structure validation of the Erg9 protein products from S. cerevisiae S288C and CEN.PK113-7D CEN.PK113-7Dd as above.

Homology modeling and structure validation: Sequences of PDB structures showing similarity with the BRP44 and FMP43 amino acid sequences were retrieved from the RCSB Protein Data Bank using different cut offs for E-values.

In another approach, Majumder and Saha used topic modeling and parse structure similarity to identify informative sentences.

The crystal structure of rhodopsin provides the first information on the three-dimensional structure of GPCRs, which now supports homology modeling studies and structure-based drug-design approaches.

The foundational concepts and methods of computational protein engineering are discussed, and an example of a computational modeling and structure-guided protein engineering workflow is provided for the design of best-in-class heterodimeric Fc with high purity and favorable biophysical properties.

As previously reported, we have sought to develop novel PKCδ-inhibitory molecules with greater specificity for PKCδ compared to essential PKC isozymes, such as PKCα, using pharmacophore modeling and structure-activity relationships (SAR) [ 47].

The presented literature review revealed that the large share of these approaches stem from economics, as these models have similar data and modeling structure than the material flow models.