Sentence examples for modeling and mutation from inspiring English sources

Modeling and mutation analyses of RrQR indicated a novel mechanism underlying the stereospecific reaction led by a characteristic interaction, explaining how optically pure (R -3-quinuclidinol is synthesized fR -3-quinuclidinolne.

Modeling and mutation analyses of the catalytic site indicated that the hydrophobicity of two residues, I167 and F212, determines the substrate-binding orientation as well as the substrate-binding affinity.

A major difference between the molecular markers mentioned is their different mutational model and mutation rates.

Reproduction is the copying of a computer model from an existing population into the new population without any change; cross-over, as shown in Fig. 3, is the genetic recombining of randomly chosen parts of two computer models; and mutation is the replacement of a randomly selected functional or terminal node with others from the same function or terminal set.

To define the precise structural features that determine the binding of distinct pathogens with CEACAMs, we have undertaken molecular modelling and mutation of the receptor molecules at previously implicated key target residues required for bacterial binding.

Mutations of miR-20 or miR-17 failed to affect oncogenesis in the Eμ-myc model, and mutations of both miR-19 miRNAs nearly abolished this oncogenic cooperation (Olive et al., 2009).

The ch-TOG-binding region on TACC3 that we identified sits in α2 in the xTACC3 structural model, and mutations in this region abrogate binding to XMAP215 (Mortuza et al., 2014).

Both molecular modeling and Q189A mutation revealed that Gln189 plays a key role in the binding.

The three-dimensional substrate-binding model and the mutation analysis indicate that the specific substrate-binding would be achieved through the interactions between hydrophobic residues and a hydrophobic substrate surface.

We identified 298 cases for which data on all prognostic models and ASXL1 mutation were available.

Based on this result two competing models, here termed as biased occupancy model and biased mutation model (fig. 1 b), both in principle are able to explain the observation of relatively higher G+C% in nuclesomal DNA.