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The prodomain of falcipain-2 was modeled in complex with the crystallographic structure of mature cathepsin B. The same homology modeling and loop modeling procedures were performed as for falcipain-2, here based on the crystallographic structures of the prodomain regions of procathepsin L, procathepsin K, and procaricain, and the solved structure of procathepsin B (PDB code 3PBH), as templates.
It performed automatically protein homology modeling and loop modeling for m357.
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Its four stages spell RIPL Recouplee, Improve, Product and business model design, and Loop.
For the 12S rRNA fragment, alignment was performed based on a collection of rodents previously aligned [ 21] and a secondary structure model (stems and loops; [ 62]).
Table 3 illustrates the difference in performance, in terms of backbone RMSD between the model and native loop, when the native structure or the model is used.
More generally Alkan et al. [ 1] studied the joint secondary structure prediction problem under three different models: 1) base pair counting, 2) stacked pair energy model, and 3) loop energy model.
More generally, Alkan et al. (2006) studied the joint secondary structure prediction problem under three different models: (i) base pair counting, (ii) stacked pair energy model and (iii) loop energy model.
The target model was later refined by side chain refinement and loop modeling to increase the communion score of each residue.
The favorable agreement between the model simulation and the loop test indicates that the developed model is valid and can be available to conduct further simulation exercise.
A Swiss engineer was inspired to create the hook-and-loop model of Velcro after walking in the mountains and noticing the extraordinary adhesive qualities of burrs that stuck to his clothing.
Both the "Protein Folding" and "Loop Modeling" tutorials demonstrate the use of distance restraints.
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