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Dynamic causal modeling analyses have been carried out previously for face-processing tasks in healthy volunteers (33 36), showing emotional modulation of effective connectivity between fusiform gyrus (FG), amygdala, and orbitofrontal cortex (OFC).
28, 29 A higher percentage of stool-based tests than was modeled may affect the projected benefits of increased screening uptake, although modeling analyses have demonstrated that the potential benefit of 10-year colonoscopy and annual fecal immunochemical testing may be comparable.
Our modeling analyses have unavoidable limitations.
Few modeling analyses have been carried out, indicating a need for further research to understand the specifics of medical nutrition and their applicability in health economic modeling.
PPR proteins bind RNA in a sequence specific manner, and recent molecular phylogenetic and modeling analyses have proposed that residues in and near the A helices may be directly involved in RNA binding [ 35].
Only a few modeling analyses have been carried out, indicating a need for further research to understand the specifics of medical nutrition and their applicability for health economic modeling.
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Modelling analyses have largely approached HIV testing from a health economics perspective to evaluate the cost effectiveness of HIV testing programs [ 4, 5, 6, 31, 37, 48, 41].
Similar results regarding control of Type I and Type II error for LOCF_ANCOVA and mixed-effects model analyses have been obtained independently [ 16, 20- 22].
While mixed model analyses have predominantly been used to identify exposure targets for effective prevention and intervention, they also represent a challenging opportunity to develop exposure assessment strategies that are both "cheap" and statistically efficient.
The longitudinal model analyses have several additional strengths over the ANCOVA, and allow for within-patient comparison of HRQoL and progression states, whereas ANCOVA only considers between-patient comparisons.
In mixed model analyses, having two or more falls was associated with greater decline in MMSE score (estimate =−0.81, standard error =0.19, P<0.0001) compared to having no fall, after adjusting for age, sex, marital status, and education.
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