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Their father primarily helped them, Nathaniel suggested, by modeling a stringent work ethic.
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We used the branch-site Model A as a stringent test to identify the sites under positive selection along the lineages of interest [ 62] and each model was run twice.
Thus, this model is a stringent clinically relevant model to evaluate this vaccine strategy.
We propose to replace the failed deterrence model with a stringent ex ante warrant requirement.
The standard PD model faces a stringent trade-off that leaves narrow margins for the design of the control parameters: the proportional gain must be large enough for supplementing the insufficient ankle stiffness but not too large for avoiding delay-promoted instability.
Commissioner Bud Selig testified that he wanted a policy modeled on stringent ones imposed by baseball on minor leaguers or by the National Football League, but he said the current policy was the best that owners managed to get during collective-bargaining negotiations in 2002.
In addition, for SNPs not selected under the log-additive model, but with a suggestion of association in either dominant or recessive models, a more stringent threshold was applied (P-value ⩽0.03) for inclusion in the replication (statistical methods described below).
Consequently, there are no free parameters in our model, allowing for a stringent experimental test.
Thus, although the model may be contrived to allow us to readily follow the T cell response, it is clearly a stringent model with aggressive tumor growth in the absence of a highly optimized therapy.
This prolongation of graft survival with DnaK is significant for a stringent model as skin transplantation in which interventions such as anti-CD8 depletion22 and immunosuppression with CTLA-4-Ig23 were incapable of prolonging graft survival.
Tumor tissue slices offer a stringent model system for preclinical evaluation of adenovirus therapies, since the slices retain a morphology and phenotype that more closely resembles the in vivo setting than cell line cultures, and this system has been shown to have utility in the evaluation of viral infectivity and replication.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com