Hybrid multi-cell models combine discrete representations of individual tumor cells with continuum representations of diffusible chemicals [70] [74] and either discrete or continuum models of the surrounding tissue.
Geomechanical modelling combined with discrete fracture network (DFN) representation of the rock mass was used to validate the rock mass strength assumptions and the failure mechanism assumed in the LE model.
At the smallest scale, the flow through stacked products in boxes was predicted using a direct model that combined discrete element (DE -CFD moDE -CFD.
This paper presents a mathematical model to describe this flow system by means of combining Discrete Element Method (DEM) with Computational Fluid Dynamics (CFD).
We developed and utilized a hybrid community modeling framework that combines discrete element techniques with reaction-diffusion equations the former for cellular force calculation and the latter for social interaction computation.
We find that experimental results are in excellent agreement with the analytical predictions and numerical simulations based on the combined discrete element and spectral element models.
In the present work, we have developed a new formalism, CADBIOM, based on guarded transitions and combined discrete abstraction to propose, for the first time, a fully integrated model for TGF-β signaling pathways.
The proposed approach combines discrete and continuous approaches in order to construct speeder and simpler reduced model.
We now combine discrete Petri net structural analysis, and stochastic and deterministic simulation and analysis of the model [ 19].
The calculations are based on a coupled numerical model, combining concepts of discrete and finite elements.
