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The items were appropriately modeled as ordinal categorical (not continuous) items.
The Likert responses on the ITBS were modeled as ordinal variables.
When some outcomes are modeled as ordinal, estimation is restricted to weighted least squares methods, thus limiting the analysis to the complete cases.
Other metabolites were categorized in three classes (< 25th percentile, 25th 74th percentile, ≥ 75th percentile) and were also modeled as ordinal variables coded using integer values (0, 1, 2) to perform trend tests.
eIF4A1, eIF4B, eIF4E and PDCD4 were modeled as ordinal values, as all four variables showed incremental unidirectional changes in hazard ratio in univariate survival models had positive log-rank trend tests across categories.
Binned risk scores were modeled as ordinal categoric variables and, in a separate analysis, as nine nominal categories; the latter is less parsimonious but allows for greater flexibility (i.e., nonlinearity) in the estimation of the individual bin risk score effects.
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Depression severity was modeled as an ordinal variable with four levels (G. Simon, personal communication).
cWald test of coefficient for body fatness modeled as an ordinal variable.
For the cadmium lead interaction, lead was also modeled as an ordinal trend variable.
dWald test of coefficient for body fatness modeled as an ordinal variable.
Abstinence time was modeled as an ordinal five-category variable (i.e., < 2, 3, 4, 5, and ≥6 days).
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