In this model, the targeted molecule of Dnmt3a would recruit additional molecules of the enzyme (maybe even the endogenous protein) to the modified region, leading to an efficient methylation of a larger genomic region adjacent to the targeted sequence (nucleation point).
In this "RNA first" model of RNP, an RNA molecule with an established function would recruit a protein to enhance activity.
Given these preferences, the new model predicted that PMA would be a significantly better kinase activator than DAG, because PMA would recruit C1B to the membrane and release kinase inhibition more efficiently.
The company would recruit people only at those ages.
We speculate about a model in which SUMO interaction with SIMs in SLX4 would promote SLX4 SUMOylation, facilitating the formation of higher-order SLX4 complexes, which, in turn, would recruit nucleases and repair proteins to stimulate DNA repair.
Ms. Welker said in an e-mail that the transition to the new recruiting model would continue, though "we anticipate having to go slower than we thought" because of uncertainties about the automatic budget cuts, known as sequestration.
A production model would be much smaller.
Years before, it had been Ned who'd recruited Gerald to pose in another client's ad — almost to be mischievous, initially, but the ad had been so successful that Gerald had made a late career of modelling for others.
In our favoured model Ana2 tetramers would help recruit Sas-6 dimers and presumably also Sas-4 molecules (Cottee et al., 2013; Hilbert et al., 2013)—in a stoichiometry and conformation that would favour cartwheel assembly.
"The traditional recruitment model is you recruit an employee, and they either sink or swim.
