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Moreover, 6h could efficiently suppress human tumor growth in mouse xenograft model without causing obvious toxicities.
The sodium salt of 9 (9Na) demonstrated potent efficacy in lowering both blood glucose and lipids in an animal model without causing significant body weight gain, a well-known side effect associated with PPARγ full agonists.
Lenaldekar was shown to induce remission in a zebrafish T-ALL model without causing substantial toxicity.
As conditional height and relative weight variables are by definition uncorrelated, they can be included in a single multivariate model without causing variance inflation.
By design, these conditional variables are uncorrelated with each other (and were also uncorrelated with weight at age 13 weeks) and therefore can be included in a single multivariable model without causing variance inflation.
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ROCK inhibitors have been widely used in animal models, such as rat and mice models, without causing major toxicity to the animals at efficient dosages [35], [56].
BDA-366, applied intraperitoneally, also prevented the growth of lung cancer cell lines and patients cells in in vivo xenograft mouse models without causing toxicity in healthy tissues.
Factors that changed model estimates by >20% without causing model instability were considered confounders and retained in the final model [ 23].
In this method, IS-NMF-based low-rank source modeling is introduced into the source model of IVA, namely, a low-rank time-frequency structure (co-occurrence among the time-frequency slots) is estimated for each source by NMF, and the frequency-wise demixing matrix is optimized taking the NMF source model into account without causing the permutation problem.
Linomide (quinoline-3-carboxamide, Roquinimex, LS 2616), is a novel, orally absorbed, immunomodulatory drug that has been shown to be effective in various models of autoimmunity without causing non-specific immunosuppression.
Mr. Duflock says he expects the storefront model to catch on without causing much harm to the tens of thousands of trading assistants who already offer such services out of their homes or cars.
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