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Anti-thrombogenicity was studied in vitro in a dynamic model with whole blood by partial thromboplastin time (PTT), platelet binding and thrombin generation, respectively, and cytotoxicity by hemolysis.
The hemocompatibility of expanded polytetrafluorethylene (ePTFE), untreated thin film nitinol (UTFN), and a surface treated superhydrophilic thin film nitinol (STFN) was compared using an in vitro circulation model with whole blood under flow conditions simulating a moderate arterial stenosis.
In this paper we present a new design of neural network model with whole stacking energy (ΔG) that enables to identify the efficacy and off target effect of siRNAs against target genes.
Hence, developed QSAR modeling workflow, build a model with whole set of descriptors to confirm that elimination of irrelevant or non informative variables is improving predictive power of given model.
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To investigate the proliferation of the tumor cells in vivo after Cripto -1 gene silencing, we employed the xenotransplant nude mice model with whole-body visualizing instrument.
Moreover, in vivo, the proliferation of the tumor cells was evaluated in xenotransplant nude mice model with whole-body visualizing instrument.
Based on our results, kinetic modeling with whole blood IF or a constant scaling factor is not recommended.
Hence, organotypic hippocampal slice cultures are an appropriate compromise between models using dissociated cell cultures and experimental in vivo models with whole living animals [ 4, 13, 22, 23].
Populus trichocarpa is a model plant with whole genome sequence available [ 32].
In addition to the regional models, we present data from two global-scale models with whole-mantle convection.
Although our data suggest that CAST overexpression/calpain inhibition in the brain is well tolerated, further models with whole-body CAST overexpression will be required to test if this is similarly well tolerated in all organs.
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