Sentence examples for model with high dose from inspiring English sources

The analysis incorporated a dose-response assessment by considering low dose pioglitazone (15 mg), high dose pioglitazone (30 mg and 45 mg), low dose rosiglitazone (2 mg and 4 mg), and high dose rosiglitazone (8 mg) as time dependent covariates in the regression model, with high dose rosiglitazone as the reference group.

In these circumstances, the optimal strategy may differ from that indicated by a homogenous mixing model, with higher dose, low-coverage strategies becoming more favorable.

In UUO rat model, long term treatment with high dose EPO or carbamylated-erythropoietin (CEPO) significantly attenuated TA/IF when compared with saline.

Furthermore, compared with the highest dose (0.8 g/kg) in Fang's report [ 16], we treated the model mice with higher dose treatment up to 5 g/kg.

Also, a recent study showed that, in a 5/6 nephrectomy model, delayed treatment with high doses of a type 1 angiotensin II receptor antagonist led to regression of glomerulosclerosis, possibly by inhibiting PAI-1 and modulating extracellular matrix turnover [53].

In our model of irradiated carotid arteries, a reduction of thrombomodulin expression around the bifurcation was seen after treatment with high dose ASA.

Patients were treated with high dose levofloxacin (1.5g/day).

Nevertheless, its anticancer efficacy is only modest with high dose.

However, silencing of adenoviral vector delivered transgenes has been observed in in vitro models of chondrogenesis with high doses of viral vector [ 19, 20].

However, these models involved acute toxicity with high doses of INH, and INH-induced liver injury in humans has very different features than such animal models.

In the present study, brine shrimp toxicity study also supports the acute toxicity study where fractions used for the in vivo studies in animal models were found safe with high doses.