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Multiple contigs mapping to different parts of the same reference were merged to give a single gene model, with gaps filled with runs of 'n'.
A specific instance of this problem occurs in metabolic modeling, although our algorithm is applicable for any biochemical network model with gaps.
An analysis of the mean distance between protein sequences using the JTT model with gaps excluded in the analysis showed that levels of sequence identity were 64.4%, much larger the 30% expected in the presence of high conservation levels.
When multiple contigs mapped to different sections of the same gene/Unigene, the sequences were condensed using a Perl script into a single model, with gaps filled by strings of 'n'.
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Almost all use some form of gap model; with the gap representing the unstable fracture [[1],[3]–[6]].
The electronic specific heat in the superconducting state can be analyzed in terms a phenomenological two BCS-like gap model with the gap widths 2Δ1/kBTc = 4.0 and 2Δ2/kBTc = 2.5, and relative weights of the molar electronic heat coefficients γ1/γn = 0.7 and γ2/γn = 0.3.
An affine gap penalty was used to model introns with gaps shorter than 5000 nt penalty-free and calibrated so that a 20,000 nt gap gets a penalty of 300.
Gap labyrinths and streaming stoppers inserted into the gaps were shown are capable to reduce the shutdown dose rate which is below the 100 μSv/h limit of personnel access and by 2 orders of magnitude less than the value in the model with straight gaps.
The numerical parametric studies conducted by varying the air-gap distance between beam and the column showed that the FE model with air gap is flexible than the model without air-gap distance.
IFW inside a shaft model with corner gap ventilation and closed roof has been reported earlier.
For the flat-punch MD simulations, rigid plates were placed at the top and bottom of the prepared PE particle model with a gap of 5 Å, as depicted in Figure 4a.
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