Sentence examples for model with disruption from inspiring English sources

However, the dual nature of oxygen was recently demonstrated using a cell model with disruption of a gene critical for mitochondrial respiration [1].

A knockout mouse model with disruption of Gnas exon 2 has been generated [Yu et al., 1998].

We use genetic mouse models with disruption in individual components of the complex to reveal hierarchical order of interactions required for AC5-Golf stability.

To study the molecular pathogenesis of microcephaly induced by DDR defects in humans, attempts have been made using mouse models with disruption of NBS1 (known as Nbn in mice) and ATR.

Two of three mouse models with disruptions in slc4a11 have also replicated the corneal defects seen in humans [ 29– 31].

For instance, the effects of two GHR knock-in models with disruptions of GHR receptor residues 391 or 569 were examined [ 26].

A mouse model with targeted disruption of Scn5a has been established [9].

Mouse models with targeted disruption of Wwox had increased spontaneous tumor incidence.

And how fast does it turn over compared to full-length TTN? Models with selective disruption and tagging of this isoform should begin to answer these questions.

The mouse models with CDKN1B disruption in combination with other genetic factors, such as Pten and Nkx3.1, have been shown to develop a range of prostate cancers, although CDKN1B inactivation alone displays no obvious neoplastic prostate lesions [ 19, 25].

Thus, animal models with congenital disruption of the GH/IGF-1 axis are unable to clearly distinguish between developmental and age-related effects of GH/IGF-1 on health.