The combination of long period data, crystal size and crystallinity measurements suggests a structure similar to the Prevorsek model, with alternating crystalline and amorphous regions along the fibre axis, and layers of amorphous material in parallel.
We addressed this problem by building ground-truth models for sugar beet N-credit and testing these models with alternate satellite sensor imagery.
We repeated identical multivariable regression models with alternate measures, except models with population-scaled measures did not control for population density.
The water molecules located at the O5 (W9andand O6 (W8atomsoms were modeled with alternate conformations (W9b and W8b) that coincide with the C5 and C6 atoms of lactose, and they were assigned occupancies of 0.4 and 0.3, respectively.
This explanation is further supported by the observation that Ser b32 on the following turn of the helix from Met b29 is modeled with alternate side-chains, indicating the presence of helical turn-to-turn interactions.
However, due to lack of mechanistic detail, the PKPD modeling (N.R. Budha et al., unpublished data) was unable to select between two indirect response models with alternate explanations for the differential LDLc response to anti-PCSK9 in statin-untreated and treated arms in the phase I study of RG7652.
Finally, multiple model specifications with alternate functional form and additional control covariates resulted in similar findings as our primary analysis (see web-only table A.5).
We then ran simulations of the time evolution of the models with alternating step inputs mimicking a sinusoidal input of this period (as this mirrors what can be implemented experimentally) to ensure that the difference in the outputs was sufficiently large to be accurately measured experimentally.
To replicate the OCP usage model with an alternate indicator for endocrine effects, age at menarche was investigated (Table 4).
Detailed fitting of synthetic binary response data containing random errors is illustrated by comparing the results of fits to the true binary model with fits to alternate, approximate equivalent circuit models.
