Sentence examples for model with adipose from inspiring English sources

In conclusion, we have established a transgenic mouse model with adipose tissue-specific expression of hSAA under the control of the aP2 promoter/enhancer.

A construct containing the mouse aP2 promoter/enhancer region was used to generate a mouse model with adipose tissue specific expression of hSAA (Figure 1).

In models with adipose mass traits, BMI or obesity as outcomes, the most strongly associated SNP was FTO rs1121980 (P < 0.001).

It is well established that PPARγ2 is important for the development of BAT since mouse models with adipose-specific PPARγ ablation have reduced or absent interscapular BAT [31].

Insulin is known to suppress lipolysis and stimulate lipogenesis in white adipose tissue (WAT) [ 17], and mouse models with reduced adipose tissue insulin signalling are protected against obesity [ 18, 19].

Moreover, in both models, the induction of fat Cnr2 expression was correlated with adipose tissue inflammation, as shown by the concurrent increase in the expression of Emr1, encoding the macrophage related marker F4/80 (Fig 1A).

Microbiota has effects beyond local tissue, with adipose tissue considered a primary target.

The tumor was easily identified at the EGJ as a protruding mass covered with adipose tissue.

Epididymis is another organ closely associated with adipose tissue.

Insulin resistance is manifested in muscle, adipose tissue, and liver and is associated with adipose tissue inflammation.

Obesity is associated with adipose tissue inflammation, characterized by macrophage infiltration into the adipose deposit [ 12].