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This knowledge transfer will enable replication of the WPCN CA model, where appropriate, in other jurisdictions.
Hence, we conservatively combined data obtained under similar condition (stirring and shear, complete occlusion obtained under different concentrations of clotting agents) by adding an additional (fixed) stratification factor to the ANOVA model, where appropriate.
To mitigate the effects of heterogeneity we have used a random effects model where appropriate.
The pooled OR was estimated using a fixed- or random-effects model, where appropriate.
Subgroup analyses will be included in the mixed-effects model where appropriate.
Interaction terms for co-morbid phenotypes and ancestry were included in the logistic regression model where appropriate.
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Addressing informational risks using a combination of privacy and security controls rather than relying on a single control such as consent or de-identification and adopting tiered access models where appropriate.
Each of the surrogate components were examined individually to identify the major intermediate species in order to improve existing kinetic models, where appropriate, and to provide a basis for examining constituent interactions in the surrogate mixture.
Both main effects and interaction terms were included in the models where appropriate.
Time-series analysis will be performed using random-effects regression models where appropriate.
Summary odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were estimated using fixed- or random-effects models where appropriate.
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