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In contrast, most clustered genes in Ifnb –/– neurons and the PD model were regulated similarly, thus indicating a higher gene signature resemblance with PD than HD.
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However, as the intrinsic frequency of VSG model is regulated by the virtual inertia, its dynamic processes which have shorter time constants such as electrical magnetic process are not taken into consideration in this model.
The Tax oncoprotein in this model is regulated by the human granzyme B promoter which targets expression primarily to activated T cells and NK cells.
Then, it is suggested that the switching between positive and negative plasticity, corresponding to that between the Hebbian and anti-Hebbian rules in our model, is regulated by the concentration of dopamine.
Moreover, these results are consistent with previous studies suggesting that inflammatory and permeability responses in this model are regulated through different mechanisms (e.g., Cho et al. 2007).
The rate of cell division in the model is regulated by auxin and a hypothetical Division Factor so that the distribution of cell divisions along the in silico root qualitatively matches the profile of mitotic activity observed experimentally.
Indeed, the transcription of at least FLO11 (one of the ORFs subjected to positive selection according to the model) is regulated by the MAPK and cAMP signalling pathways [ 123] and changes in the expression levels of this gene strongly affect colony morphology [ 124].
It is known that different xenograft models are regulated by different pathways, and that the necessary absence of a fully functional immune system in the host will also make these models somewhat artificial.
These variations in amino acid concentration with cycle stage and pregnancy suggest that levels in large animal models are regulated, which is in contrast to our observations in the human where no differences were obtained between the proliferative and secretory stages.
Additionally, we analyzed a modified model whereby hapX and sreA were regulated transcriptionally by iron, and all other interactions are the same.
According to the regulated nucleosome mobility model, chromatin is regulated by factors that control the equilibrium between nucleosomes with low and high mobility [27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com