Prostate carcinoma metastasis in a mouse model was prevented by a synthetic urokinase inhibitor [ 29].
Salmonella-induced tissue damage in the organ model was prevented by a culture supernatant from the L. paracasei strain.
Instead, the increase in spontaneous activity induced by oxaliplatin in this model was prevented by the voltage-gated Na+ channel blocker tetrodotoxin.
Gross and colleagues have shown that similar reduction in podocytes occurs after 6 months of streptozotocin (STZ) diabetes in rats [ 14] and that loss of podocytes in this model was prevented by treatment with the angiotensin converting enzyme inhibitor, trandolopril.
The lymphatic metastasis in this model was prevented by a neutralising VEGF-D antibody that blocked binding of this growth factor to both VEGFR-2 and VEGFR-3 (Achen et al, 2000; Stacker et al, 2001).
Accordingly, both acute nociception and its sensitization in chronic pain models are prevented by systemic or focal spinal inhibition of MGL activity.
Gashed application landscapes, heterogenic systems and consequently different inconsistent product data models are preventing an efficient product development especially across different stages of the product lifecycle (Sharma and Gao (2006)).
In our model, these abnormalities were prevented upon reconstitution with wild-type BMMCs.
None of these behaviors was observed in the linear analyses, where failure was insensitive to the form of the damage model and where structural instabilities were prevented from occurring.
In an animal model this was prevented by C5a-blocking antibodies [ 101].
