Just-identified models are median-unbiased, even with weak instruments (Angrist and Pischke, 2009, p. 209) and also deserve some consideration.
The log transformed expressed gene values were median centered, and then the standardized residuals of the hybridization block ANOVA model were themselves median centered and used for all subsequent gene expression analysis.
Bias and inaccuracy of each model were assessed by median prediction error (MDPE) and median absolute prediction error (MDAPE), respectively.The M/P propofol Cp in the 4 PK models revealed bias in all 3 compartmental models during the bolus and short infusion regimens.
The key variables in the logistic regression model were population density, median household income, proportion of residents who are immigrants from malaria-endemic countries, and sex.
Residuals from fitting the model were relatively low, with a median of 0.11.
Instead of a sliding window, normalized probe intensities falling within the exons of each gene model were compared using the pseudo median and random label statistics.
The predictors considered in the model were: age at diagnosis (age ≤ median age 64, age > median age 64); ER-alpha status (ER ≤ 3 considered negative, ER > 3 are positive); node status (positive, negative); SRAP (low SRAP ≤ 76.67, high SRAP > 76.67); all two, three and four-way interactions involving SRAP.
In all 47 cases the difference in c-AIC between HIV-Wm and the best-fitting previously described empirical model was sufficiently large (median 125 points, range 13.3 259.5) to render the latter model not credible, with R HIV-Wm,best existing empiR HIV-Wmdel) >50 for every tested dataset.
In all 11 cases the difference in c-AIC between HIV-Bm and the best-fitting previously described empirical model was sufficiently large (median 38.42 points, range 6.5 345.5) to suggest that previous empirical models fitted the data poorly, with R HIV-Bm,best existing empiR HIV-Bmdel) >25 for every tested dataset.
A unique aspect of the data used to estimate the model was the availability of median barrier placement and median cross-slope data, two elements not commonly included in roadway inventory data files.
