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For calibrating a rate-dependent visco-plastic self-consistent polycrystal model we needed only to measure the material's initial texture and to fit power-law and saturation-hardening laws to our tensile data.
In defining the prediction model, we needed to identify the PDZ positions that affect binding specificity of every ligand position.
In this model, we needed both cooperativity and positive feedback to achieve gradient-induced polarization observed in the experiments (Fig. 7A); the normalized levels of active Cdc42 ([C42a]norm) were plotted along the length of the cell.
In order to create a prediction model, we needed to (i) discard source-specific phenomena, and (ii) add a normalization step which would reduce the effect of different intensity levels where the trend was maintained.
In order to incorporate behavior into the model, we needed to include the possibility for cell differentiation so that the organism could include sensor and motor cells in addition to its hidden neural cells.
Having established the mathematical model, we needed to estimate the parameter values and to check whether our model was able to reproduce the experimental observed Hog1 response to osmotic stress.
Similar(48)
That's not the economic model we need to act on climate change.
"If we are going to break the drug dealer's model, we need to smash demand," Keenan said.
"But beyond being a role model, we need somebody who is physically fit to run the country in the next six years".
"What these tenants have accomplished is extraordinary, and it's a model we need to replicate: pressure from within and resources from without".
To determine whether the company has a viable business model, we need more financial reporting transparency from Groupon and less marketing hype.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com