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The ability of 7 metastatic melanoma primary cultures to transmigrate across our in vitro barrier model was screened in preliminary experiments to estimate if they had different ability to transpass the BBB model (data not shown).
The new refined pharmacophore model was screened against two conformational ensembles of D1 ligands that were generated with both MMFF(S) 51 (MOE) 41 and OPLS 52 (MacroModel) 53 force fields, using Born solvation (water).
The new refined pharmacophore model was screened against two conformational ensembles of D2 ligands (structures shown in Figure 1; for a full account of the set, see reference 28) generated with both MOE 58 (mmffs) 71 and MacroModel 72 (OPLS) 73 software and Born solvation (water).
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A panel of 10 SCLC cell lines models was screened for MET alterations for this study.
Included in the model were screening approach, screening tool, and intervention, and the model was adjusted for age, sex, and baseline AUDIT score.
Models were screened for influential cases by addressing standardized residuals and Cook's distance.
Additionally, the models were screened for influential cases by addressing standardized residuals and Cook's distance.
With that in mind, Neda has advocated that models be screened for eating disorders, but not that they be prohibited from working based on a size and weight limit.
Further, the order in which the models are screened does not influence the final number of models that matches all phenotypes.
The resulting 98 gene models were screened using BLASTN and BLASTP against homology to known protein coding sequences and an array of other problems on the genome browser.
These models were screened using the full human genome and databases of promoter sequences from human and several other mammalian species.
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