Botha argues that the best funds provide far more than capital, helping to guide startups through early pitfalls, assist with marketing and introductions, etc. Zachary says there's a place for a different model, particularly very early stage angel funding with less handholding to allow funds to invest in a lot of different companies.
Non-malignant human mammary epithelial cells (HMECs) provide an exciting in vitro model of very early breast carcinogenesis.
PrPSc deposition in ME7 model begins very early in the incubation period (60 dpi) appearing within the hippocampus cortex, thalamus and paraterminal body.
Recent finding revealed that mouse is a suitable model for very early safety assessment since earlier identification of preclinical toxicities are generally predictive of human toxicity and could save time, money, and effort spent [ 16].
Könnyű and co-workers have attempted to fill the gap between purely mathematical, "toy" modeling of very early evolution and the physico-chemical realm within which such evolution may have proceeded.
Among the Sunnis, this model took effect very early and persisted until modern times.
As a matter of fact, a practical clinical model would compare very early to late-treated patients.
Dynamic cerebral autoregulation is improved in healthy volunteers after a four-hour lipopolysaccharide (LPS) infusion, a human-experimental model of the very early stages of sepsis.
To investigate the possible gene expression change in our ConA-induced hepatitis model at a very early stage, we performed a gene chip study by using the Affymetrix probe dataset which includes totally 45101 probes.
We suggest that the HART model represents a very early stage of pre-hypertrophy in which VEGF signalling has not stabilized, the decrease in the NM population representing an initial mechanism to prevent fibrosis by inhibition of extracellular matrix.
