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ISPOR's model validation guidelines emphasize the value of quantitatively assessing goodness of fit [ 34]; however, the specific choice of quantitative measure to use is not obvious.
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In accordance with these guidelines, external model validation was performed and a range of model statistics were calculated for a comprehensive performance analysis.
Mechanistic interpretation and proper model validation are requirements of the OECD guidelines for valid (Q SAR models [14].
This method has been validated to meet FDA validation guidelines.
Finally, we emphasize the importance of data collection and model validation to ensure, amongst others, compliance to regulatory guidelines.
Our results cover two distinct aspects: (1) Control-oriented model validation results, where we show that a measure of size of the validated model set is connected to the size of the model-based controller set that robustly stabilizes the model set, leading to validation design guidelines.
Model validation is a necessary step before numerical simulation can be finally used in practice, e.g. for checking existing design guidelines.
Model validation.
Symbolic Software Model Validation.
Model validation using independent datasets.
We used 5-fold cross-validation for model validation.
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