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In each model, two stable states of synaptic strength/weight resulted.
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More striking, however, is the result that the model supports two stable equilibria for a range of R0<1. Figure 2C represents the parasite prevalence in terms of the force of infection, confirming qualitative agreement with previous studies [14].
In the case of Medea, the age-structured model has two stable equilibria at which the frequencies of the wild genotype are 1 and 0, respectively.
In the case of EU, the age-structured model has two stable equilibria Es1 and Es2, where the frequency of the wild genotype is 1 (constructs are lost) and at some low level (constructs are at high frequency), respectively.
Given these two features, both models have two stable states and a bistable region in the phase diagram.
We analyze the fast evolutionary game model and obtain two stable equilibria.
With the model we identify two stable latency programs, corresponding to a resting and proliferating cell.
When s > 0 and/or c > 0 the model has three equilibria: two stable ones E0 and E1, and an unstable one Eu.
Three-dimensional structures of several Cys-rhEPOs were generated using homology modeling, and three stable Cys-rhEPOs were selected on the basis of model stability in molecular dynamics simulation and surface accessibility of the inserted cysteine.
It is interesting to note that our model also displays the existence of two stable states as the crossregulation model although it describes the interaction of different cell types and mechanisms.
For high KDf corresponding to the open loop system, the model exhibits bistability manifesting as two stable steady states across a range of αf values (Supplementary Fig. 13b).
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