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We investigated the serum proteomic changes and potential biomarkers in an RSV-infected mouse pneumonia model treated with QFOL.
The immunocytochemistry to detect IL-6 expression and immunofluorescence assay suggested that induced apoptosis occurs in experimentally induced in vitro arthritis model treated with NLCs-MTX.
With an APC-mimetic biomaterial scaffold, the researchers achieved greater expansion of primary mouse and human T cells than with existing methods; and they demonstrated the approach's potential in a mouse lymphoma model treated with chimeric antigen receptor-expressing T cells (CAR-T cells) that are engineered to home in on and destroy lymphoma cells.
On the other hand, the aneurysm model treated with unmodified EVAL showed that the cavity was almost filled with EVAL mass and that fibroblasts and macrophages filled a narrow space between the EVAL mass and the cavity wall.
The objective of our study was to evaluate the behavior of ovine chondrocytes and bone marrow stromal cells (BMSC) on a matrix comprising type-I, -II, and -III collagen in vitro, and the healing of chondral defects in an ovine model treated with the matrix, either unseeded or seeded with autologous chondrocytes, combined with microfracture treatment.
Cejkove et al. [8] also reported a good response in an alkali-burned rabbit corneal model treated with CACICOL20.
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It is not known how many olfactory receptor neurons should be intact to maintain olfaction in mouse models treated with 3-methylindole.
Tanaka et al. [27] also reported that while the protective effect was seen following treatment with UFH and LMWH, it was not seen in the sepsis models treated with argatroban.
However, the decrease in AR+ bacilli was far less pronounced in guinea pigs compared to the mouse infection models treated with the same drugs.
These results are similar to in vivo calvarial and in vitro cell culture models treated with PTH [43], as well as murine models of constitutively-active PTHR1 receptor [44], [60].
Genetic changes are frequently observed in experimental animal models treated with AA.
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