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To develop a genetic model to study the function of GMAP-210 in vivo, we identified its closest relative in Drosophila melanogaster, dGMAP.
The genetic tractability of Drosophila melanogaster makes this organism an ideal model to study the function of presenilin.
Therefore, C. elegans is an ideal model to study the function of the MAGI-1 protein in associative learning and neural plasticity.
This result provides evidence for using pig as a model to study the function of hJAB1 and disease relevant with JAB1.
It is therefore possible that pig could be more valuable as a model to study the function of JAB1 than the traditionally used mouse or rat models.
The use of one cell type, the epithelial cells, to reproduce acinar differentiation is a simplified yet efficient model to study the function of luminal epithelial cells in vitro.
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In this study, we made use of the vertebrate Danio rerio as an additional vertebrate model organism to study the function of parkin.
Durkin et al. [17] has generated a DLC1-deficient mouse model to study the biological functions of DLC1.
Our study introduces an additional vertebrate model to study in vivo the function of Tie-2 in development and disease.
The goals of this work were: (1) to employ an appropriate animal model to study etv7 function, and (2) to determine the function of etv7 during development.
These data further confirm the usefulness of our transgenic model to study Nrf2 function.
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