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The Oct1 KO mice provide a model to investigate the function of Oct1 systemically.
Silencing of genes inserted near telomeres provides a model to investigate the function of heterochromatin.
Kanamori et al. [ 36, 40] used a mouse myocardial infarction model to investigate the function of autophagy in ischemic remodeling.
Therefore, we used microvilli of a colon cancer cell line (Caco2) as a model to investigate the function of Myo3A in vivo.
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We are using xenograft and transgenic mouse models to investigate the function of EMT-related miRNAs.
The adult Drosophila gut is a useful model to investigate the function and regulation of the diffuse endocrine system.
It is thus an ideal model to investigate the role of XPA in nervous system function.
We next developed a pre-clinical model suitable to investigate the function of IL-12R in human lung adenocarcinoma.
To investigate the function of Arl5, we have used Drosophila melanogaster as a model system.
To investigate the function of Nrbp1 in vivo, we constructed a conditional knockout mouse model.
This model has also been used to investigate the functions of upstream signalling and transcriptional regulators.
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